Time & Location
Autumn Quarter 2013
1.5 credits, weeks 6-10 (Oct 31 - Dec 3)
Tuesdays and Thursdays
Place: FHCRC B1-072-074
A five week graduate survey course concentrating on biochemical mechanisms of gene transcription. The course will cover broad range of transcriptional regulation including: Mechanisms of transcriptional initiation (Steve Hahn); Regulation of transcription by chromatin (Toshio Tsukiyama); Transcriptional regulation, development and diseases in mammals (Steve Tapscott).
Lecture dates, topics and lecturer are listed below. Copies of all the readings are available in the eReserves (select the tab above).
Lectures will be ready for downloading the day after the lecture and can also be found in eReserves.
A copy of the entire lecture schedule is available for download below.
Lecture 1 - Oct 31, 2013
Transcriptional Regulatory Mechanisms in Bacteria
Lecture 2 - Nov 5, 2013
RNA Pol II Transcription and Regulation I
Lecture 3 - Nov 7, 2013
RNA Pol II Transcription and Regulation II
Lecture 4 - Nov 12, 2013
Homework#1 to be handed out.
Lecture 5 - Nov 14, 2013
Chromatin and Transcription: General Overview
Lecture 6 - Nov 19, 2013
Histone Modifying Enzymes
Homework #1 due
Lecture 7 - Nov 21, 2013
ATP-dependent Chromatin Remodeling Factors
Homework #2 to be handed out
lecture 8 - Nov 26, 2013
Promoter-specific and Regional Regulation of Transcription
Homework #1 to be returned
Lecture 9 - Dec 3, 2013
Dynamic and Compex Patterns of Gene Expression
Homework #2 due
Homework #3 handed out (due Dec 10 and can be dropped off at Mailstop C3-168 or emailed to firstname.lastname@example.org.
Homework #2 and #3 can be picked up after 12/10 (#2) and 12/17 (#3) at A1-175 (#2) and C3-168 (#3).