Online Training
- Enhancing Humane Science/Improving Animal Research (from Johns Hopkins CAAT)

A free online course offers an overview on the practice of and approaches to humane animal experimentation. It addresses experimental design (statistics & sample size determination), humane endpoints, environmental enrichment, post-surgical care and more.
Web Resources
- Altweb from Johns Hopkins
Global clearinghouse for information on alternatives to animal testing - Animal Welfare Institute
The Animal Welfare Institute is a non-profit organization founded to reduce the pain inflicted on animals including improving the housing and handling of animals used for experimentation and pushing for the development of animal research alternatives. - AWIC Animal Welfare Information Center (USDA)
The Animal Welfare Information Center (AWIC) is mandated by the Animal Welfare Act (AWA) to provide information for improved animal care and use in research, testing, teaching, and exhibition. - Fund for the Replacement of Animals in Medical Experiments (FRAME)
Supports efforts to reduce the numbers of animals used through better science and better experimental design, and to refine procedures so that the suffering of any animals necessarily used is minimised. - IACUC Training and Learning Consortium
IACUC.ORG is an information resource for members and staff of institutional animal care and use committees - Institute for Laboratory Animal Research (ILAR)
ILAR's mission is to evaluate and disseminate information on issues related to the scientific, technological, and ethical use of animals and related biological resources in research, testing, and education. - John Hopkins Center for Alternatives to Animal Testing
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) has worked to find new methods to replace the use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to eliminate pain and distress. - National Centre for the Replacement, Refinement, and Reduction of Animals in Research
The National Centre for the Replacement, Refinement and Reduction of Animals in Research provides a UK focus for the promotion, development and implementation of the 3Rs in animal research and testing. - Norwegian Reference Centre for Laboratory Animal Science & Alternatives
The Centre provides information on laboratory animal science and alternatives to the use of animals in research, teaching and school dissection classes. - University of California, Davis Center for Animal Alternatives
The UCDavis Center for Animal Alternatives places special emphasis on disseminating up-to-date information concerning animal alternatives through every level of public and private education.
Free Online Book
Read a free, full-text version of the 1992 edition of W.M.S. Russell and R.L. Burch's The Principles of Humane Experimental Technique in which they classified humane techniques under the headings of replacement, reduction, and refinement--now commonly known as the three Rs.
You can also read the original, 1959, first edition of The Principles of Humane Experimental Technique" free online at Google Books.
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