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Con 533 The Dynamic Chromosome 2010  

Graduate course with limited enrollment and pre-requisites, Sept-Nov 2010
Last Updated: Aug 28, 2014 URL: Print Guide RSS UpdatesEmail Alerts

Class Schedule Print Page


Problems are handed out at the end of each Henikoff lecture and must be handed in at the beginning of next class session. Any problem set handed in late or sent by e-mail will be downgraded.


Time & Location

Autumn Quarter 2010

1.5 credits, weeks 1-5

Tuesdays and Thursdays

3:20-4:40 p.m.

FHCRC, Weintraub Bld, Room B1-072/074/076

Steve Henikoff will be away 10/19


Course Description

This course is a graduate level introduction to the chromosome, viewing it as the ultimate organelle. Topics this year will focus on the functions and evolution of chromosomal elements as well as the mechanisms that ensure the maintenance and propagation of chromosomes. The class will use a combination of lecture, literature review, and in-class discussion to explore genetic, biochemical, and cytological methods for defining our current knowledge about chromosomes. The course requires students to have taken undergraduate cell biology, biochemistry and genetics. Active participation in discussion is required.

Course registration is limited to 30 students.


Class Schedule

Go to "Lectures and Papers" page to download the lecture files and get links to the assigned papers and reviews. Go to "Problem sets" to download the problem assigned after each lecture and the answer for the problem assigned for the previous lecture.

  • Thursday, Sep 30, 2010: Lecture 1 (Henikoff)
    Chromosomes and genomes
  • Tuesday, Oct 5, 2010: Lecture 2 (Henikoff)
  • Thursday, Oct 7, 2010: Lecture 3 (Henikoff)
    Replication and repair
  • Tuesday, Oct 12, 2010: Lecture 4 (Henikoff)
    Mitosis and Meiosis
  • Thursday, Oct 14, 2010: Lecture 5 (Henikoff)
  • Tuesday, Oct 19, 2010: Lecture 6 (Harmit Malik)
    Mobile Elements
  • Thursday, Oct 21, 2010: Lecture 7 (Henikoff)
  • Tuesday, Oct 26, 2010: Lecture 8 (Henikoff)
    Nuclear Organization
  • Thursday, Oct 28, 2010: Lecture 9 (Henikoff)
  • Tuesday, Nov 2, 2010: Lecture 10 (Henikoff)
    Chromosome evolution

Subject Guide

Steve Henikoff
Contact Info
1100 Fairview Ave. N
Rm. A1-162
Phone: (206) 667-4515
Send Email

Guest Lecturers

Harmit Malik -


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