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Conj 533 The Dynamic Chromosome   Tags: biggins, conj533, henikoff, malik  

Last Updated: Feb 20, 2013 URL: http://libguides.fhcrc.org/conj533 Print Guide RSS UpdatesEmail Alerts

Class Schedule Print Page
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Time & Location

Autumn Quarter 2012

1.5 credits, weeks 1-5 (Sept 25 - Oct 25)

Tuesdays and Thursdays

Times: 3:20-4:40

Place: FHCRC B1-072

 

Course Description

This course is a graduate level introduction to the chromosome, viewing it as the ultimate organelle. Topics this year will focus on the functions and evolution of chromosomal elements as well as the mechanisms that ensure the maintenance and propagation of chromosomes. The class will use a combination of lecture, literature review, and in-class discussion to explore genetic, biochemical, and cytological methods for defining our current knowledge about chromosomes. The course requires students to have taken undergraduate cell biology, biochemistry and genetics. Active participation in discussion is required.

Course registration is limited to 30 students.  PLEASE EMAIL MICHELE KARANTSAVELOS (mkarants@fhcrc.org) FOR ADD CODE.  SUE BIGGINS IS NOT INVOLVED IN ASSIGNING THEM.

 

Lecture Schedule

Lecture dates, topics and lecturer are listed below. Copies of all the readings are available in the eReserves (select the tab above).

Lectures will be ready for downloading the day after the lecture and can also be found in eReserves.

 

Lecture 1 - Sept 25, 2012

Chromosome Introduction
Sue Biggins

 

Lecture 2 - Sept 27, 2012

Replication
Sue Biggins

 

Lecture 3 - Oct 2, 2012

Epigenetics
Steve Henikoff

 

Lecture 4 - Oct 4, 2012

Nuclear Organization
Steve Henikoff 

 

Lecture 5 - Oct 9, 2012

Cohesion and Condensation
Sue Biggins

 

Lecture 6 - Oct 11, 2012

Centromeres
Sue Biggins 

 

Lecture 7 - Oct 16, 2012

Telomeres
Sue Biggins

 

Lecture 8 - Oct 18, 2012

Evolution of mobile elements and chromosome structure
Harmit Malik

 

Lecture 9 - Oct 23, 2012

Genome Integrity
Sue Biggins

 

Lecture 10 - Oct 25, 2012

Meiosis
Sue Biggins

 

Course Organizer

Course Organizer:

Sue Biggins, Ph.D.
sbiggins@fhcrc.org
206-667-1351

Guest Lecturers:

Steve Henikoff
steveh@fhcrc.org
206-667-4515

Harmit Malik
hsmalik@fhcrc.org
206-667-5204

 

Grading

Grades will be based on problem sets and class participation with the following distribution.

Problem Set 1, 20%

Problem Set 2, 20%

Problem Set 3, 20%

Problem Set 4, 30%

Participation, 10%

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